Oligonucleotides process development

• Raw material selection

  Chemical modification and conjugation process

• Process development and validation

Quality Research

• Formulation and establishment of quality standard

  Impurities study

• Raw material testing

  Structure confirmation of the API

• Quality control of the process

  Stability study

• Quality test

  Reference preparation and calibration

Analytical method development, transfer and validation

• Analytical method development

  Method transfer and validation

• Sequence

Drug Registration Support

• CMC material support for IND application

  NDA application material support